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Mathematical and experimental analysis of localization of anti-tumour antibody–enzyme conjugates

Considerable research has been aimed at improving the efficacy of chemotherapeutic agents for cancer therapy. A promising two-step approach that is designed to minimize systemic drug toxicity while maximizing activity in tumours employs monoclonal antibody (mAb)–enzyme conjugates for the activation...

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Detalles Bibliográficos
Autores principales:	Jackson, T L, Lubkin, S R, Siemers, N O, Kerr, D E, Senter, P D, Murray, J D
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363130/ https://www.ncbi.nlm.nih.gov/pubmed/10468291 http://dx.doi.org/10.1038/sj.bjc.6690592

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