Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer

Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women. Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association. The issue of AT and late onset sporadic breast cancer remained unresolv...

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Detalles Bibliográficos
Autores principales: Bebb, D G, Yu, Z, Chen, J, Telatar, M, Gelmon, K, Phillips, N, Gatti, R A, Glickman, B W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363154/
https://www.ncbi.nlm.nih.gov/pubmed/10471049
http://dx.doi.org/10.1038/sj.bjc.6690630
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author Bebb, D G
Yu, Z
Chen, J
Telatar, M
Gelmon, K
Phillips, N
Gatti, R A
Glickman, B W
author_facet Bebb, D G
Yu, Z
Chen, J
Telatar, M
Gelmon, K
Phillips, N
Gatti, R A
Glickman, B W
author_sort Bebb, D G
collection PubMed
description Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women. Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association. The issue of AT and late onset sporadic breast cancer remained unresolved. We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations. No mutations were found. © 1999 Cancer Research Campaign
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spelling pubmed-23631542009-09-10 Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer Bebb, D G Yu, Z Chen, J Telatar, M Gelmon, K Phillips, N Gatti, R A Glickman, B W Br J Cancer Regular Article Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women. Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association. The issue of AT and late onset sporadic breast cancer remained unresolved. We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations. No mutations were found. © 1999 Cancer Research Campaign Nature Publishing Group 1999-08 /pmc/articles/PMC2363154/ /pubmed/10471049 http://dx.doi.org/10.1038/sj.bjc.6690630 Text en Copyright © 1999 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Bebb, D G
Yu, Z
Chen, J
Telatar, M
Gelmon, K
Phillips, N
Gatti, R A
Glickman, B W
Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer
title Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer
title_full Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer
title_fullStr Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer
title_full_unstemmed Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer
title_short Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer
title_sort absence of mutations in the atm gene in forty-seven cases of sporadic breast cancer
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363154/
https://www.ncbi.nlm.nih.gov/pubmed/10471049
http://dx.doi.org/10.1038/sj.bjc.6690630
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