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Inhibition of I κ B-α phosphorylation at serine and tyrosine acts independently on sensitization to DNA damaging agents in human glioma cells

Molecular mechanisms and/or intrinsic factors controlling cellular radiosensitivity are not fully understood in mammalian cells. The recent studies have suggested that nuclear factor κB (NF-κB) is one of such factors. The activation and regulation of NF-κB are tightly controlled by IκB-α, a cellular...

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Detalles Bibliográficos
Autores principales: Miyakoshi, J, Yagi, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363178/
https://www.ncbi.nlm.nih.gov/pubmed/10638962
http://dx.doi.org/10.1054/bjoc.1999.0872