Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese

We investigated levels of p53 protein expression in Japanese patients with oesophageal squamous cell carcinoma. A significantly larger proportion of heavy alcohol drinkers and cigarette smokers was evident in the p53-positive group. The combination of drinking and smoking was associated with a high...

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Autores principales: Saeki, H, Ohno, S, Araki, K, Egashira, A, Kawaguchi, H, Ikeda, Y, Morita, M, Kitamura, K, Sugimachi, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363236/
https://www.ncbi.nlm.nih.gov/pubmed/10839309
http://dx.doi.org/10.1054/bjoc.1999.1212
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author Saeki, H
Ohno, S
Araki, K
Egashira, A
Kawaguchi, H
Ikeda, Y
Morita, M
Kitamura, K
Sugimachi, K
author_facet Saeki, H
Ohno, S
Araki, K
Egashira, A
Kawaguchi, H
Ikeda, Y
Morita, M
Kitamura, K
Sugimachi, K
author_sort Saeki, H
collection PubMed
description We investigated levels of p53 protein expression in Japanese patients with oesophageal squamous cell carcinoma. A significantly larger proportion of heavy alcohol drinkers and cigarette smokers was evident in the p53-positive group. The combination of drinking and smoking was associated with a high frequency of p53 protein accumulation. © 2000 Cancer Research Campaign
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spelling pubmed-23632362009-09-10 Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese Saeki, H Ohno, S Araki, K Egashira, A Kawaguchi, H Ikeda, Y Morita, M Kitamura, K Sugimachi, K Br J Cancer Regular Article We investigated levels of p53 protein expression in Japanese patients with oesophageal squamous cell carcinoma. A significantly larger proportion of heavy alcohol drinkers and cigarette smokers was evident in the p53-positive group. The combination of drinking and smoking was associated with a high frequency of p53 protein accumulation. © 2000 Cancer Research Campaign Nature Publishing Group 2000-06 /pmc/articles/PMC2363236/ /pubmed/10839309 http://dx.doi.org/10.1054/bjoc.1999.1212 Text en Copyright © 2000 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Saeki, H
Ohno, S
Araki, K
Egashira, A
Kawaguchi, H
Ikeda, Y
Morita, M
Kitamura, K
Sugimachi, K
Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese
title Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese
title_full Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese
title_fullStr Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese
title_full_unstemmed Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese
title_short Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese
title_sort alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the japanese
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363236/
https://www.ncbi.nlm.nih.gov/pubmed/10839309
http://dx.doi.org/10.1054/bjoc.1999.1212
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