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Immune selection in neoplasia: towards a microevolutionary model of cancer development
The dual properties of genetic instability and clonal expansion allow the development of a tumour to occur in a microevolutionary fashion. A broad range of pressures are exerted upon a tumour during neoplastic development. Such pressures are responsible for the selection of adaptations which provide...
Autores principales: | Pettit, S J, Seymour, K, O'Flaherty, E, Kirby, J A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363247/ https://www.ncbi.nlm.nih.gov/pubmed/10864195 http://dx.doi.org/10.1054/bjoc.2000.1206 |
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