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Immune selection in neoplasia: towards a microevolutionary model of cancer development

The dual properties of genetic instability and clonal expansion allow the development of a tumour to occur in a microevolutionary fashion. A broad range of pressures are exerted upon a tumour during neoplastic development. Such pressures are responsible for the selection of adaptations which provide...

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Detalles Bibliográficos
Autores principales: Pettit, S J, Seymour, K, O'Flaherty, E, Kirby, J A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363247/
https://www.ncbi.nlm.nih.gov/pubmed/10864195
http://dx.doi.org/10.1054/bjoc.2000.1206

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