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Anti-tumour activity of tachykinin NK(1)receptor antagonists on human glioma U373 MG xenograft
Astrocytes harbour functional receptors to many neurotransmitters, including substance P (SP), an undecapeptide belonging to the tachykinin family of peptide transmitters. SP activates malignant glial cells to induce cytokine release and proliferation, both responses being relevant for tumour progre...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363296/ https://www.ncbi.nlm.nih.gov/pubmed/10646908 http://dx.doi.org/10.1054/bjoc.1999.0946 |