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Anti-tumour activity of tachykinin NK(1)receptor antagonists on human glioma U373 MG xenograft

Astrocytes harbour functional receptors to many neurotransmitters, including substance P (SP), an undecapeptide belonging to the tachykinin family of peptide transmitters. SP activates malignant glial cells to induce cytokine release and proliferation, both responses being relevant for tumour progre...

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Detalles Bibliográficos
Autores principales: Palma, C, Bigioni, M, Irrissuto, C, Nardelli, F, Maggi, C A, Manzini, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363296/
https://www.ncbi.nlm.nih.gov/pubmed/10646908
http://dx.doi.org/10.1054/bjoc.1999.0946