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Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its presence does not apparently affect hMSH2 function. © 2000 Cancer Research Campaign

Detalles Bibliográficos
Autores principales:	Palicio, M, Blanco, I, Tórtola, S, González, I, Marcuello, E, Brunet, J, Lluis, F, González-Aguilera, J J, Peinado, M A, Capella, G
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363304/ https://www.ncbi.nlm.nih.gov/pubmed/10682661 http://dx.doi.org/10.1054/bjoc.1999.0959

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