Idarubicinol myelotoxicity: a comparison of in vitro data with clinical outcome in patients treated with high-dose idarubicin

We evaluated in vitro the toxicity of idarubicin and its active metabolite idarubicinol on haematopoietic progenitors, using human umbilical cord blood and peripheral blood progenitors to obtain dose–response curves. We treated 16 patients with poor prognosis lymphoma in a phase I–II trial of high-d...

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Detalles Bibliográficos
Autores principales: Corsini, C, Ghielmini, M, Mancuso, P, Tealdo, F, Paolucci, M, Zucchetti, M, Ferrucci, P F, Cocorocchio, E, Mezzetti, M, Mori, A, Riggi, M, D'Incalci, M, Martinelli, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363340/
https://www.ncbi.nlm.nih.gov/pubmed/10682659
http://dx.doi.org/10.1054/bjoc.1999.0957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363340/
https://www.ncbi.nlm.nih.gov/pubmed/10682659
http://dx.doi.org/10.1054/bjoc.1999.0957

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