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Characterization of antigen-presenting properties of tumour cells using virus-specific cytotoxic T lymphocytes

Immunotherapy of tumours by induction of tumour-specific cytotoxic T-lymphocytes (CTLs) will only be effective for tumours with a functional antigen processing and presentation machinery. However, many tumours are known to down-regulate expression of major histocompatibility complex (MHC) class I mo...

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Detalles Bibliográficos
Autores principales: Spierings, D C J, Agsteribbe, E, Wilschut, J, Huckriede, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363376/
https://www.ncbi.nlm.nih.gov/pubmed/10780529
http://dx.doi.org/10.1054/bjoc.1999.1081