Cargando…

The constitutive level of vascular endothelial growth factor (VEGF) is more important than hypoxia-induced VEGF up-regulation in the angiogenesis of human melanoma xenografts

Angiogenesis of tumours might develop as a result of environmental conditions, such as hypoxia, and/or as a result of genetic alterations specific for tumour cells. The relative contributions of these mechanisms were investigated by comparing the in vivo expression of vascular endothelial growth fac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Danielsen, T, Rofstad, E K
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363386/ https://www.ncbi.nlm.nih.gov/pubmed/10789719 http://dx.doi.org/10.1054/bjoc.2000.1173

Ejemplares similares

Hypoxia-induced metastasis of human melanoma cells: involvement of vascular endothelial growth factor-mediated angiogenesis
por: Rofstad, E K, et al.
Publicado: (1999)

Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma.
por: Rofstad, E. K., et al.
Publicado: (1998)

VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours
por: Ohta, Y, et al.
Publicado: (1999)

Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts
por: Gaustad, Jon-Vidar, et al.
Publicado: (2017)

Localization of VEGF to Vascular ECM Is an Important Aspect of Tumor Angiogenesis
por: You, Weon-Kyoo, et al.
Publicado: (2017)

Inhibition of angiogenesis and tumour growth by VEGF121–toxin conjugate: differential effect on proliferating endothelial cells
por: Wild, R, et al.
Publicado: (2000)

Prognostic value of vascular endothelial growth factor (VEGF) in head and neck squamous cell carcinomas
por: Mineta, H, et al.
Publicado: (2000)

Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues
por: Akagi, K, et al.
Publicado: (2000)

Expression of vascular endothelial growth factor (VEGF) and its mRNA in uterine cervical cancers
por: Fujimoto, J, et al.
Publicado: (1999)

The era of anti-vascular endothelial growth factor (VEGF) drugs in ophthalmology, VEGF and anti-VEGF therapy
por: Pożarowska, Dorota, et al.
Publicado: (2016)

Fetal Vegf Genotype is More Important for Abortion Risk than Mother Genotype
por: Yalcintepe, Sinem Atik, et al.
Publicado: (2014)

Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease
por: Mayer, Gert
Publicado: (2011)

The Effect and Mechanism of Vascular Endothelial Growth Factor (VEGF) on Tumor Angiogenesis in Gallbladder Carcinoma
por: XU, Dongqing, et al.
Publicado: (2019)

Vascular Endothelial Growth Factor-D (VEGF-D): An Angiogenesis Bypass in Malignant Tumors
por: Bokhari, Syeda Mahak Zahra, et al.
Publicado: (2023)

Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression
por: Gaustad, Jon-Vidar, et al.
Publicado: (2016)

Anti-VEGF Agents for Ocular Angiogenesis and Vascular Permeability
por: Kimoto, Kenichi, et al.
Publicado: (2012)

Growth rates or radiobiological hypoxia are not correlated with local metabolite content in human melanoma xenografts with similar vascular network.
por: Kroeger, M., et al.
Publicado: (1995)

Vascular endothelial growth factor (VEGF) expression is a prognostic factor for radiotherapy outcome in advanced carcinoma of the cervix
por: Loncaster, J A, et al.
Publicado: (2000)

Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling
por: Wittig, Christine, et al.
Publicado: (2015)

The Role of Vascular Endothelial Growth Factor (VEGF) and p53 Status for Angiogenesis in Gastric Cancer
por: Joo, Young Eun, et al.
Publicado: (2002)

Diabetic macular edema: it is more than just VEGF
por: Singer, Michael A., et al.
Publicado: (2016)

Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
por: Pidgeon, G P, et al.
Publicado: (2001)

EDIL3 and VEGF Synergistically Affect Angiogenesis in Endothelial Cells
por: Niu, Xuping, et al.
Publicado: (2023)

Inhibitory Effects of Anti-VEGF Antibody on the Growth and Angiogenesis of Estrogen-induced Pituitary Prolactinoma in Fischer 344 Rats: Animal Model of VEGF-targeted Therapy for Human Endocrine Tumors
por: Miyajima, Katsuhiro, et al.
Publicado: (2010)

Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression
por: Wang, Min, et al.
Publicado: (2019)

Does vascular endothelial growth factor (VEGF) predict local relapse and survival in radiotherapy-treated node-negative breast cancer?
por: Linderholm, B, et al.
Publicado: (1999)

Hypoxia-induced treatment failure in advanced squamous cell carcinoma of the uterine cervix is primarily due to hypoxia-induced radiation resistance rather than hypoxia-induced metastasis
por: Rofstad, E K, et al.
Publicado: (2000)

Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern.
por: Rofstad, E. K.
Publicado: (1994)

Multiple Roles for VEGF in Non-Melanoma Skin Cancer: Angiogenesis and Beyond
por: Johnson, Kelly E., et al.
Publicado: (2012)

Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis
por: Han, Kyu-Yeon, et al.
Publicado: (2016)

Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
por: Cheng, Jiao, et al.
Publicado: (2019)

Fructose promotes angiogenesis by improving vascular endothelial cell function and upregulating VEGF expression in cancer cells
por: Cui, Yanfen, et al.
Publicado: (2023)

tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis
por: Savage, Aaron M., et al.
Publicado: (2019)

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
por: Papadopoulos, Nicholas, et al.
Publicado: (2012)

Overexpression of vascular endothelial growth factor (VEGF) receptors on keratinocytes in psoriasis: regulated by calcium independent of VEGF
por: Man, Xiao-Yong, et al.
Publicado: (2008)

Vascular Endothelial Growth Factor: Much More than an Angiogenesis Factor
por: Senger, Donald R.
Publicado: (2010)

Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis
por: Evans, Ian M., et al.
Publicado: (2017)

MiR-103 regulates the angiogenesis of ischemic stroke rats by targeting vascular endothelial growth factor (VEGF)
por: Shi, Fu-Ping, et al.
Publicado: (2018)

Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma
por: Gammons, M V, et al.
Publicado: (2014)

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling
por: Stefanini, Marianne O., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_a22vqv5skfa6puvou8ocfbmaaq