Cargando…

Increased uracil misincorporation in lymphocytes from folate-deficient rats

The development of certain human cancers has been linked with inadequate intake of folates. The effects of folate deficiency in vivo on DNA stability (strand breakage, misincorporated uracil and oxidative base damage) in lymphocytes isolated from rats fed a diet deficient in folic acid was determine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duthie, S J, Grant, G, Narayanan, S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363426/ https://www.ncbi.nlm.nih.gov/pubmed/11076664 http://dx.doi.org/10.1054/bjoc.2000.1481

Ejemplares similares

MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA
por: Wu, Ming-Tsung, et al.
Publicado: (2021)

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation
por: Paone, A, et al.
Publicado: (2014)

Misincorporation Proteomics Technologies: A Review
por: Steele, Joel R., et al.
Publicado: (2021)

Disease-associated inosine misincorporation into RNA hinders translation
por: Schroader, Jacob H, et al.
Publicado: (2022)

Characterization of Nucleotide Misincorporation Patterns in the Iceman's Mitochondrial DNA
por: Olivieri, Cristina, et al.
Publicado: (2010)

Excessive Folic Acid Mimics Folate Deficiency in Human Lymphocytes
por: Alnabbat, Khadijah I., et al.
Publicado: (2022)

Effect of paternal folate deficiency on placental folate content and folate receptor α expression in rats
por: Kim, Hye Won, et al.
Publicado: (2011)

Errors in translational decoding: tRNA wobbling or misincorporation?
por: Ou, Xumin, et al.
Publicado: (2019)

Temporal Patterns of Nucleotide Misincorporations and DNA Fragmentation in Ancient DNA
por: Sawyer, Susanna, et al.
Publicado: (2012)

Dynamic Basis for dG•dT misincorporation via tautomerization and ionization
por: Kimsey, Isaac J., et al.
Publicado: (2018)

Misincorporation by RNA polymerase is a major source of transcription pausing in vivo
por: James, Katherine, et al.
Publicado: (2017)

Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae
por: Plateau, Pierre, et al.
Publicado: (2017)

Mechanism of genome instability mediated by human DNA polymerase mu misincorporation
por: Guo, Miao, et al.
Publicado: (2021)

In crystallo observation of three metal ion promoted DNA polymerase misincorporation
por: Chang, Caleb, et al.
Publicado: (2022)

A structural determinant in the uracil DNA glycosylase superfamily for the removal of uracil from adenine/uracil base pairs
por: Lee, Dong-Hoon, et al.
Publicado: (2015)

Folate status, folate-related genes and serum miR-21 expression: Implications for miR-21 as a biomarker
por: Beckett, Emma Louise, et al.
Publicado: (2015)

Removal of Misincorporated Ribonucleotides from Prokaryotic Genomes: An Unexpected Role for Nucleotide Excision Repair
por: Vaisman, Alexandra, et al.
Publicado: (2013)

Conditional accumulation of toxic tRNAs to cause amino acid misincorporation
por: Zimmerman, Stephanie M, et al.
Publicado: (2018)

Quantum Tunnelling Effects in the Guanine-Thymine Wobble Misincorporation via Tautomerism
por: Slocombe, Louie, et al.
Publicado: (2022)

How the misincorporation of ribonucleotides into genomic DNA can be both harmful and helpful to cells
por: Potenski, Catherine J., et al.
Publicado: (2014)

Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair
por: Ghodgaonkar, Medini Manohar, et al.
Publicado: (2013)

Folate Deficiency Increased Lipid Accumulation and Leptin Production of Adipocytes
por: Chan, Chun-Wai, et al.
Publicado: (2022)

Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase
por: Schormann, N., et al.
Publicado: (2013)

Mechanism of intestinal folate transport during folate deficiency in rodent model
por: Wani, Nissar Ahmad, et al.
Publicado: (2012)

Identification of Lysine Misincorporation at Asparagine Position in Recombinant Insulin Analogs Produced in E. coli
por: Stadnik, Dorota, et al.
Publicado: (2019)

A SMRT approach for targeted amplicon sequencing of museum specimens (Lepidoptera)—patterns of nucleotide misincorporation
por: D’Ercole, Jacopo, et al.
Publicado: (2021)

The active site of TthPolX is adapted to prevent 8-oxo-dGTP misincorporation
por: Garrido, Patricia, et al.
Publicado: (2014)

Influences of Folate Supplementation on Homocysteine and Cognition in Patients with Folate Deficiency and Cognitive Impairment
por: Hama, Yuka, et al.
Publicado: (2020)

A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily
por: Sang, Pau Biak, et al.
Publicado: (2015)

Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects
por: Hildebrand, Erica M., et al.
Publicado: (2016)

Phase I dose-escalation and pharmacokinetic study of a novel folate analogue AG2034
por: Bissett, D, et al.
Publicado: (2001)

Folate deficiency affects histone methylation
por: Garcia, Benjamin A., et al.
Publicado: (2016)

Detection of Genomic Uracil Patterns
por: Békési, Angéla, et al.
Publicado: (2021)

Folate Deficiency Induces Neural Stem Cell Apoptosis by Increasing Homocysteine In Vitro
por: Zhang, Xu-Mei, et al.
Publicado: (2009)

CD3 directed bispecific antibodies induce increased lymphocyte–endothelial cell interactions in vitro
por: Molema, G, et al.
Publicado: (2000)

A novel class of lipophilic quinazoline-based folic acid analogues: cytotoxic agents with a folate-independent locus
por: Skelton, L A, et al.
Publicado: (1999)

Periconceptional Folate Deficiency and Implications in Neural Tube Defects
por: Safi, J., et al.
Publicado: (2012)

Serum folate, homocysteine and colorectal cancer risk in women: a nested case–control study
por: Kato, I, et al.
Publicado: (1999)

Dietary Intake of Folate and Assessment of the Folate Deficiency Prevalence in Slovenia Using Serum Biomarkers
por: Pravst, Igor, et al.
Publicado: (2021)

Correction: Steele et al. Misincorporation Proteomics Technologies: A Review. Proteomes 2021, 9, 2
por: Steele, Joel R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5hg13ra1a3outknnes68kf96n9