Screening breast cancer patients for Norwegian ATM mutations

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483 Norwegian breast cancer patients were screened for six different ataxia telangiectasia mutated (ATM) mutations previously found to account for 83% of the disease alleles in Norwegian ataxia telangiectasia (AT) patients. Only one carrier was found. These results provide no evidence in favour of a...

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Autores principales: Laake, K, Vu, P, Andersen, T I, Erikstein, B, Kåresen, R, Lønning, P E, Skovlund, E, Børresen-Dale, A L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363448/
https://www.ncbi.nlm.nih.gov/pubmed/11104561
http://dx.doi.org/10.1054/bjoc.2000.1519
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author Laake, K
Vu, P
Andersen, T I
Erikstein, B
Kåresen, R
Lønning, P E
Skovlund, E
Børresen-Dale, A L
author_facet Laake, K
Vu, P
Andersen, T I
Erikstein, B
Kåresen, R
Lønning, P E
Skovlund, E
Børresen-Dale, A L
author_sort Laake, K
collection PubMed
description 483 Norwegian breast cancer patients were screened for six different ataxia telangiectasia mutated (ATM) mutations previously found to account for 83% of the disease alleles in Norwegian ataxia telangiectasia (AT) patients. Only one carrier was found. These results provide no evidence in favour of an excess risk of breast cancer associated with heterozygosity for classical AT mutations, but remain consistent with a maximum 2.4-fold increased risk. © 2000 Cancer Research Campaign http://www.bjcancer.com
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spelling pubmed-23634482009-09-10 Screening breast cancer patients for Norwegian ATM mutations Laake, K Vu, P Andersen, T I Erikstein, B Kåresen, R Lønning, P E Skovlund, E Børresen-Dale, A L Br J Cancer Regular Article 483 Norwegian breast cancer patients were screened for six different ataxia telangiectasia mutated (ATM) mutations previously found to account for 83% of the disease alleles in Norwegian ataxia telangiectasia (AT) patients. Only one carrier was found. These results provide no evidence in favour of an excess risk of breast cancer associated with heterozygosity for classical AT mutations, but remain consistent with a maximum 2.4-fold increased risk. © 2000 Cancer Research Campaign http://www.bjcancer.com Nature Publishing Group 2000-12 /pmc/articles/PMC2363448/ /pubmed/11104561 http://dx.doi.org/10.1054/bjoc.2000.1519 Text en Copyright © 2000 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Laake, K
Vu, P
Andersen, T I
Erikstein, B
Kåresen, R
Lønning, P E
Skovlund, E
Børresen-Dale, A L
Screening breast cancer patients for Norwegian ATM mutations
title Screening breast cancer patients for Norwegian ATM mutations
title_full Screening breast cancer patients for Norwegian ATM mutations
title_fullStr Screening breast cancer patients for Norwegian ATM mutations
title_full_unstemmed Screening breast cancer patients for Norwegian ATM mutations
title_short Screening breast cancer patients for Norwegian ATM mutations
title_sort screening breast cancer patients for norwegian atm mutations
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363448/
https://www.ncbi.nlm.nih.gov/pubmed/11104561
http://dx.doi.org/10.1054/bjoc.2000.1519
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