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Phase I study of irinotecan and raltitrexed in patients with advanced astrointestinal tract adenocarcinoma

To determine the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of irinotecan and raltitrexed given as sequential short infusions every 3 weeks, 33 patients with pretreated gastrointestinal adenocarcinoma (31 colorectal, 2 oesophagogastric) entered this open label dose-escalation st...

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Detalles Bibliográficos
Autores principales:	Ford, H E R, Cunningham, D, Ross, P J, Rao, S, Aherne, G W, Benepal, T S, Price, T, Massey, A, Vernillet, L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363476/ https://www.ncbi.nlm.nih.gov/pubmed/10901362 http://dx.doi.org/10.1054/bjoc.2000.1192

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