Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines

We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloi...

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Autores principales: Parle-McDermott, A, McWilliam, P, Tighe, O, Dunican, D, Croke, D T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363537/
https://www.ncbi.nlm.nih.gov/pubmed/10952775
http://dx.doi.org/10.1054/bjoc.2000.1330
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author Parle-McDermott, A
McWilliam, P
Tighe, O
Dunican, D
Croke, D T
author_facet Parle-McDermott, A
McWilliam, P
Tighe, O
Dunican, D
Croke, D T
author_sort Parle-McDermott, A
collection PubMed
description We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloid A, the human homologue of yeast ribosomal S28 and the p32 subunit of human pre-mRNA splicing factor SF2. Expression of confirmed differences were also analysed in other metastatic cell lines. © 2000 Cancer Research Campaign
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spelling pubmed-23635372009-09-10 Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines Parle-McDermott, A McWilliam, P Tighe, O Dunican, D Croke, D T Br J Cancer Regular Article We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloid A, the human homologue of yeast ribosomal S28 and the p32 subunit of human pre-mRNA splicing factor SF2. Expression of confirmed differences were also analysed in other metastatic cell lines. © 2000 Cancer Research Campaign Nature Publishing Group 2000-09 2000-08-17 /pmc/articles/PMC2363537/ /pubmed/10952775 http://dx.doi.org/10.1054/bjoc.2000.1330 Text en Copyright © 2000 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Parle-McDermott, A
McWilliam, P
Tighe, O
Dunican, D
Croke, D T
Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
title Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
title_full Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
title_fullStr Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
title_full_unstemmed Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
title_short Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
title_sort serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363537/
https://www.ncbi.nlm.nih.gov/pubmed/10952775
http://dx.doi.org/10.1054/bjoc.2000.1330
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