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No SMAD4 hypermethylation in colorectal cancer

The chromosome region 18q21 is frequently deleted in colorectal cancers. Three candidate tumour suppressor genes, DCC, SMAD4 and SMAD2, map to this region. The SMAD4(DPC4) gene was recently identified as a candidate pancreatic cancer suppressor gene. It is also a gene for juvenile polyposis tumour p...

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Detalles Bibliográficos
Autores principales:	Roth, S, Laiho, P, Salovaara, R, Launonen, V, Aaltonen, L A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363563/ https://www.ncbi.nlm.nih.gov/pubmed/10993648 http://dx.doi.org/10.1054/bjoc.2000.1387

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