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Chromosome instability in fibroblasts derived from Li–Fraumeni syndrome families without TP53 mutations
The mean in vitro lifespan of dermal fibroblast strains derived from cancer-affected individuals belonging to families conforming to the classical Li-Fraumeni-syndrome or the Li-Fraumeni-like syndrome (LF strains), but in whom no TP53 mutation has been found, was not significantly different to that...
Autores principales: | Boyle, J M, Spreadborough, A, Greaves, M J, Birch, J M, Scott, D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363597/ https://www.ncbi.nlm.nih.gov/pubmed/11027425 http://dx.doi.org/10.1054/bjoc.2000.1444 |
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