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Effect of P-glycoprotein on flavopiridol sensitivity

Flavopiridol is the first potent inhibitor of cyclin-dependent kinases (CDKs) to enter clinical trials. Little is known about mechanisms of resistance to this agent. In order to determine whether P-glycoprotein (Pgp) might play a role in flavopiridol resistance, we examined flavopiridol sensitivity...

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Detalles Bibliográficos
Autores principales:	Boerner, S A, Tourne, M E, Kaufmann, S H, Bible, K C
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363628/ https://www.ncbi.nlm.nih.gov/pubmed/11355953 http://dx.doi.org/10.1054/bjoc.2000.1688

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