CDX2 mutations do not account for juvenile polyposis or Peutz–Jeghers syndrome and occur infrequently in sporadic colorectal cancers

Peutz–Jeghers syndrome (PJS) and juvenile polyposis (JPS) are both characterized by the presence of hamartomatous polyps and increased risk of malignancy in the gastrointestinal tract. Mutations of the LKB1 and SMAD4 genes have been shown recently to cause a number of PJS and JPS cases respectively,...

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Detalles Bibliográficos
Autores principales: Woodford-Richens, K L, Halford, S, Rowan, A, Bevan, S, Aaltonen, L A, Wasan, H, Bicknell, D, Bodmer, W F, Houlston, R S, Tomlinson, I P M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363639/
https://www.ncbi.nlm.nih.gov/pubmed/11355940
http://dx.doi.org/10.1054/bjoc.2001.1800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363639/
https://www.ncbi.nlm.nih.gov/pubmed/11355940
http://dx.doi.org/10.1054/bjoc.2001.1800

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