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Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

An analysis of the activity of compounds tested in pre-clinical in vivo and in vitro assays by the National Cancer Institute's Developmental Therapeutics Program was performed. For 39 agents with both xenograft data and Phase II clinical trials results available, in vivo activity in a particula...

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Detalles Bibliográficos
Autores principales:	Johnson, J I, Decker, S, Zaharevitz, D, Rubinstein, L V, Venditti, J M, Schepartz, S, Kalyandrug, S, Christian, M, Arbuck, S, Hollingshead, M, Sausville, E A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363645/ https://www.ncbi.nlm.nih.gov/pubmed/11355958 http://dx.doi.org/10.1054/bjoc.2001.1796

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