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Childhood cancer incidence in a cohort of twin babies

We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (Standardized Incidence Ratio (SIR) 79; 95% Confidence Interval (CI) 39–120). Pooled analysis...

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Detalles Bibliográficos
Autores principales: Murphy, M F G, Whiteman, D, Hey, K, Griffith, M, Gill, L, Goldacre, M J, Vincent, T J, Bunch, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363658/
https://www.ncbi.nlm.nih.gov/pubmed/11384093
http://dx.doi.org/10.1054/bjoc.2001.1799
Descripción
Sumario:We studied childhood cancer incidence in a population-based twin cohort using record linkage to the National Registry of Childhood Tumours. After correcting for mortality, an incidence deficit was observed (Standardized Incidence Ratio (SIR) 79; 95% Confidence Interval (CI) 39–120). Pooled analysis with data from published cohort studies indicates a similar significant incidence reduction (SIR 81, 95% CI 67–96). Further studies are warranted. © 2001 Cancer Research Campaign http://www.bjcancer.com