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Modulation of docetaxel-induced apoptosis and cell cycle arrest by all- trans retinoic acid in prostate cancer cells

We report that all- trans retinoic acid (ATRA) enhanced the toxicity of docetaxel against DU145 and LNCaP prostate cancer cells, and that the nature of the interaction between ATRA and docetaxel was highly synergistic. Docetaxel-induced apoptotic cell death was associated with phosphorylation and he...

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Detalles Bibliográficos
Autores principales:	Nehmé, A, Varadarajan, P, Sellakumar, G, Gerhold, M, Niedner, H, Zhang, Q, Lin, X, Christen, R D
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363662/ https://www.ncbi.nlm.nih.gov/pubmed/11384110 http://dx.doi.org/10.1054/bjoc.2001.1818

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