Risk of breast cancer among Norwegian women with visual impairment

Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons. Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally...

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Detalles Bibliográficos
Autores principales: Kliukiene, J, Tynes, T, Andersen, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363754/
https://www.ncbi.nlm.nih.gov/pubmed/11161406
http://dx.doi.org/10.1054/bjoc.2000.1617
Descripción
Sumario:Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons. Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally blind women was 0.64 (95% CI = 0.21–1.49, 5 cases only), and for those who became blind before age of 65, the SIR was 0.51 (95% CI = 0.11–1.49). Our findings give support to the ‘melatonin hypothesis’. © 2001 Cancer Research Campaign http://www.bjcancer.com

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