Risk of breast cancer among Norwegian women with visual impairment

Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons. Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally...

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Detalles Bibliográficos
Autores principales: Kliukiene, J, Tynes, T, Andersen, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363754/
https://www.ncbi.nlm.nih.gov/pubmed/11161406
http://dx.doi.org/10.1054/bjoc.2000.1617
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author Kliukiene, J
Tynes, T
Andersen, A
author_facet Kliukiene, J
Tynes, T
Andersen, A
author_sort Kliukiene, J
collection PubMed
description Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons. Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally blind women was 0.64 (95% CI = 0.21–1.49, 5 cases only), and for those who became blind before age of 65, the SIR was 0.51 (95% CI = 0.11–1.49). Our findings give support to the ‘melatonin hypothesis’. © 2001 Cancer Research Campaign http://www.bjcancer.com
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spelling pubmed-23637542009-09-10 Risk of breast cancer among Norwegian women with visual impairment Kliukiene, J Tynes, T Andersen, A Br J Cancer Regular Article Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons. Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally blind women was 0.64 (95% CI = 0.21–1.49, 5 cases only), and for those who became blind before age of 65, the SIR was 0.51 (95% CI = 0.11–1.49). Our findings give support to the ‘melatonin hypothesis’. © 2001 Cancer Research Campaign http://www.bjcancer.com Nature Publishing Group 2001-02 /pmc/articles/PMC2363754/ /pubmed/11161406 http://dx.doi.org/10.1054/bjoc.2000.1617 Text en Copyright © 2001 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Kliukiene, J
Tynes, T
Andersen, A
Risk of breast cancer among Norwegian women with visual impairment
title Risk of breast cancer among Norwegian women with visual impairment
title_full Risk of breast cancer among Norwegian women with visual impairment
title_fullStr Risk of breast cancer among Norwegian women with visual impairment
title_full_unstemmed Risk of breast cancer among Norwegian women with visual impairment
title_short Risk of breast cancer among Norwegian women with visual impairment
title_sort risk of breast cancer among norwegian women with visual impairment
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363754/
https://www.ncbi.nlm.nih.gov/pubmed/11161406
http://dx.doi.org/10.1054/bjoc.2000.1617
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