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A role for chromosomal instability in the development of and selection for radioresistant cell variants
Chromosome instability is a common occurrence in tumour cells. We examined the hypothesis that the elevated rate of mutation formation in unstable cells can lead to the development of clones of cells that are resistant to the cancer therapy. To test this hypothesis, we compared chromosome instabilit...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363756/ https://www.ncbi.nlm.nih.gov/pubmed/11207043 http://dx.doi.org/10.1054/bjoc.2000.1604 |