Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal

In a population-based study, causes of death were traced of 418 deceased breast cancer patients diagnosed in 1960–1979 who survived at least 10 years after diagnosis. The pattern of causes of death in these patients was compared with the general female population using standardized mortality ratios...

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Autores principales: Louwman, W J, Klokman, W J, Coebergh, J W W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363789/
https://www.ncbi.nlm.nih.gov/pubmed/11237394
http://dx.doi.org/10.1054/bjoc.2000.1616
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author Louwman, W J
Klokman, W J
Coebergh, J W W
author_facet Louwman, W J
Klokman, W J
Coebergh, J W W
author_sort Louwman, W J
collection PubMed
description In a population-based study, causes of death were traced of 418 deceased breast cancer patients diagnosed in 1960–1979 who survived at least 10 years after diagnosis. The pattern of causes of death in these patients was compared with the general female population using standardized mortality ratios (SMRs). Of 418 patients surviving at least 10 years, 196 (47%) died from breast cancer and 50 (12%) died from another cancer. The SMR for breast cancer was 15.8 (95% CI: 13.1–18.8) 10–14 years after diagnosis; it was still 4.7 (95% CI: 2.6–7.8) after 20 years. Overall mortality was higher than expected 10–14 years after diagnosis (SMR: 1.3; 95% CI: 1.1–1.5), but lower after more than 20 years (SMR: 0.6; 95% CI: 0.4–0.7). Despite a normal (or even improved) life expectancy for breast cancer patients 20 years after diagnosis the risk of dying from this disease remained elevated. © 2001 Cancer Research Campaign http://www.bjcancer.com
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spelling pubmed-23637892009-09-10 Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal Louwman, W J Klokman, W J Coebergh, J W W Br J Cancer Regular Article In a population-based study, causes of death were traced of 418 deceased breast cancer patients diagnosed in 1960–1979 who survived at least 10 years after diagnosis. The pattern of causes of death in these patients was compared with the general female population using standardized mortality ratios (SMRs). Of 418 patients surviving at least 10 years, 196 (47%) died from breast cancer and 50 (12%) died from another cancer. The SMR for breast cancer was 15.8 (95% CI: 13.1–18.8) 10–14 years after diagnosis; it was still 4.7 (95% CI: 2.6–7.8) after 20 years. Overall mortality was higher than expected 10–14 years after diagnosis (SMR: 1.3; 95% CI: 1.1–1.5), but lower after more than 20 years (SMR: 0.6; 95% CI: 0.4–0.7). Despite a normal (or even improved) life expectancy for breast cancer patients 20 years after diagnosis the risk of dying from this disease remained elevated. © 2001 Cancer Research Campaign http://www.bjcancer.com Nature Publishing Group 2001-03 /pmc/articles/PMC2363789/ /pubmed/11237394 http://dx.doi.org/10.1054/bjoc.2000.1616 Text en Copyright © 2001 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Louwman, W J
Klokman, W J
Coebergh, J W W
Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
title Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
title_full Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
title_fullStr Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
title_full_unstemmed Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
title_short Excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
title_sort excess mortality from breast cancer 20 years after diagnosis when life expectancy is normal
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363789/
https://www.ncbi.nlm.nih.gov/pubmed/11237394
http://dx.doi.org/10.1054/bjoc.2000.1616
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