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Phase I trial and pharmacological study of a 3-hour paclitaxel infusion in children with refractory solid tumours: a SFOP study
The maximum tolerated dose of paclitaxel administered by 24-hour continuous infusion in children is known. Short infusion might offer equivalent antitumour efficacy and reduced haematological toxicity, without increasing the allergic risk. Our aims were to determine the maximum tolerated dose and th...
Autores principales: | Doz, F, Gentet, J C, Pein, F, Frappaz, D, Chastagner, P, Moretti, S, Vassal, G, Arditti, J, Tellingen, O Van, Iliadis, A, Catalin, J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363793/ https://www.ncbi.nlm.nih.gov/pubmed/11237379 http://dx.doi.org/10.1054/bjoc.2000.1637 |
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