Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells

Ras is frequently mutated in cancer, and novel therapies are being developed to target Ras signalling. To identify non-invasive surrogate markers of Ras activation and inhibition, we used(31)P magnetic resonance spectroscopy (MRS) and investigated NIH 3T3 cells compared to a mutant ras transfected c...

Descripción completa

Detalles Bibliográficos
Autores principales: Ronen, S M, Jackson, L E, Beloueche, M, Leach, M O
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363797/
https://www.ncbi.nlm.nih.gov/pubmed/11237392
http://dx.doi.org/10.1054/bjoc.2000.1663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363797/
https://www.ncbi.nlm.nih.gov/pubmed/11237392
http://dx.doi.org/10.1054/bjoc.2000.1663

Ejemplares similares