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Codon 89 polymorphism in the human 5 α -reductase gene in primary breast cancer
The enzyme human steroid 5-α reductase type II (SRD5A2) and androgen receptor (AR) are critical mediators of androgen action, suggesting a potential role in hormonally related cancers. The SRD5A2 gene harbours two frequent polymorphic sites, one in the coding region, at codon 89 of exon 1, where val...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363825/ https://www.ncbi.nlm.nih.gov/pubmed/11259089 http://dx.doi.org/10.1054/bjoc.2000.1681 |