Cargando…
Codon 89 polymorphism in the human 5 α -reductase gene in primary breast cancer
The enzyme human steroid 5-α reductase type II (SRD5A2) and androgen receptor (AR) are critical mediators of androgen action, suggesting a potential role in hormonally related cancers. The SRD5A2 gene harbours two frequent polymorphic sites, one in the coding region, at codon 89 of exon 1, where val...
Autores principales: | Scorilas, A, Bharaj, B, Giai, M, Diamandis, E P |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363825/ https://www.ncbi.nlm.nih.gov/pubmed/11259089 http://dx.doi.org/10.1054/bjoc.2000.1681 |
Ejemplares similares
-
Human kallikrein gene 5 (KLK5) expression is an indicator of poor prognosis in ovarian cancer
por: Kim, H, et al.
Publicado: (2001) -
Cloning of a gene (SR-A1), encoding for a new member of the human Ser/Arg-rich family of pre-mRNA splicing factors: overexpression in aggressive ovarian cancer
por: Scorilas, A, et al.
Publicado: (2001) -
A49T, V89L and TA repeat polymorphisms of steroid 5α-reductase type II and breast cancer risk in Japanese women
por: Yang, Chunxia, et al.
Publicado: (2002) -
The significance of p53 codon 72 polymorphism for the development of cervical adenocarcinomas
por: Andersson, S, et al.
Publicado: (2001) -
The promoter and the enhancer region of the KLK 3 (prostate specific antigen) gene is frequently mutated in breast tumours and in breast carcinoma cell lines
por: Majumdar, S, et al.
Publicado: (1999)