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Codon 89 polymorphism in the human 5 α -reductase gene in primary breast cancer

The enzyme human steroid 5-α reductase type II (SRD5A2) and androgen receptor (AR) are critical mediators of androgen action, suggesting a potential role in hormonally related cancers. The SRD5A2 gene harbours two frequent polymorphic sites, one in the coding region, at codon 89 of exon 1, where val...

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Detalles Bibliográficos
Autores principales: Scorilas, A, Bharaj, B, Giai, M, Diamandis, E P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363825/
https://www.ncbi.nlm.nih.gov/pubmed/11259089
http://dx.doi.org/10.1054/bjoc.2000.1681

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