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Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line
Local growth of osteosarcoma involves destruction of host bone by proteolytic mechanisms and/or host osteoclast activation. Osteoclast formation and activity are regulated by osteoblast-derived factors such as the osteoclast differentiating factor, receptor activator of NF-κB ligand (RANKL) and the...
Autores principales: | Mackie, P S, Fisher, J L, Zhou, H, Choong, P F M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363848/ https://www.ncbi.nlm.nih.gov/pubmed/11286476 http://dx.doi.org/10.1054/bjoc.2000.1679 |
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