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Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562
Dexrazoxane combined with doxorubicin (+ 5-fluorouracil + cyclophosphamide – the FAC regime) leads to a significant decrease in doxorubicin cardiotoxicity and a significant increase in median survival time for patients with advanced breast cancer responsive to FAC. The reason for this increase in su...
Autores principales: | Sargent, J M, Williamson, C J, Yardley, C, Taylor, C G, Hellmann, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363849/ https://www.ncbi.nlm.nih.gov/pubmed/11286477 http://dx.doi.org/10.1054/bjoc.2001.1697 |
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