Characterization of BIS20x3, a bi-specific antibody activating and retargeting T-cells to CD20-positive B-cells

This paper describes a bi-specific antibody, which was called BIS20x3. It retargets CD3ɛ-positive cells (T-cells) to CD20-positive cells and was obtained by hybrid–hybridoma fusion. BIS20x3 could be isolated readily from quadroma culture supernatant and retained all the signalling characteristics as...

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Detalles Bibliográficos
Autores principales: Withoff, S, Bijman, M N A, Stel, A J, Delahaye, L, Calogero, A, Jonge, M W A de, Kroesen, B J, Leij, L de
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363855/
https://www.ncbi.nlm.nih.gov/pubmed/11308263
http://dx.doi.org/10.1054/bjoc.2000.1707

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