Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?

Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, i...

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Detalles Bibliográficos
Autores principales: Skliris, G P, Carder, P J, Lansdown, M R J, Speirs, V
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363860/
https://www.ncbi.nlm.nih.gov/pubmed/11308260
http://dx.doi.org/10.1054/bjoc.2001.1721
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author Skliris, G P
Carder, P J
Lansdown, M R J
Speirs, V
author_facet Skliris, G P
Carder, P J
Lansdown, M R J
Speirs, V
author_sort Skliris, G P
collection PubMed
description Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, immunohistochemical detection of ERβ in archival breast tumours. © 2001 Cancer Research Campaignhttp://www.bjcancer.com
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spelling pubmed-23638602009-09-10 Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling? Skliris, G P Carder, P J Lansdown, M R J Speirs, V Br J Cancer Regular Article Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, immunohistochemical detection of ERβ in archival breast tumours. © 2001 Cancer Research Campaignhttp://www.bjcancer.com Nature Publishing Group 2001-04 /pmc/articles/PMC2363860/ /pubmed/11308260 http://dx.doi.org/10.1054/bjoc.2001.1721 Text en Copyright © 2001 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Skliris, G P
Carder, P J
Lansdown, M R J
Speirs, V
Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
title Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
title_full Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
title_fullStr Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
title_full_unstemmed Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
title_short Immunohistochemical detection of ERβ in breast cancer: towards more detailed receptor profiling?
title_sort immunohistochemical detection of erβ in breast cancer: towards more detailed receptor profiling?
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363860/
https://www.ncbi.nlm.nih.gov/pubmed/11308260
http://dx.doi.org/10.1054/bjoc.2001.1721
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AT lansdownmrj immunohistochemicaldetectionoferbinbreastcancertowardsmoredetailedreceptorprofiling
AT speirsv immunohistochemicaldetectionoferbinbreastcancertowardsmoredetailedreceptorprofiling

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