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Chronic hypoxia modulates tumour cell radioresponse through cytokine-inducible nitric oxide synthase

Chronic hypoxia up-regulated the mRNA and protein expression of inducible nitric oxide synthase (iNOS) in EMT-6 tumour cells exposed to interferon (IFN)-gamma and interleukin (IL)-I beta. Low concentrations of cytokines (1 unit ml(−1)) in 1% but not in 21% oxygen induced a remarkable increase in NO...

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Detalles Bibliográficos
Autores principales:	Berge, D L Van den, Ridder, M De, Verovski, V N, Janssens, M Y, Monsaert, C, Storme, G A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363861/ https://www.ncbi.nlm.nih.gov/pubmed/11308264 http://dx.doi.org/10.1054/bjoc.2000.1719

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