Role of chance in familial aggregation of colorectal cancer

A prospective population-based study recorded family trees of 77 colorectal cancer patients younger than 50 years of age. Using mathematical modeling of population age-incidence data, we estimate that 1 (95% confidence limits 0 and 3) of these families is expected to meet the Amsterdam criteria I fo...

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Autores principales: Katballe, N, Bentzen, S M, Christensen, M, Wikman, F P, Ørntoft, T, Laurberg, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363862/
https://www.ncbi.nlm.nih.gov/pubmed/11308258
http://dx.doi.org/10.1054/bjoc.2000.1717
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author Katballe, N
Bentzen, S M
Christensen, M
Wikman, F P
Ørntoft, T
Laurberg, S
author_facet Katballe, N
Bentzen, S M
Christensen, M
Wikman, F P
Ørntoft, T
Laurberg, S
author_sort Katballe, N
collection PubMed
description A prospective population-based study recorded family trees of 77 colorectal cancer patients younger than 50 years of age. Using mathematical modeling of population age-incidence data, we estimate that 1 (95% confidence limits 0 and 3) of these families is expected to meet the Amsterdam criteria I for HNPCC due to chance clustering of colorectal cancer. © 2001 Cancer Research Campaign http://www.bjcancer.com
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spelling pubmed-23638622009-09-10 Role of chance in familial aggregation of colorectal cancer Katballe, N Bentzen, S M Christensen, M Wikman, F P Ørntoft, T Laurberg, S Br J Cancer Regular Article A prospective population-based study recorded family trees of 77 colorectal cancer patients younger than 50 years of age. Using mathematical modeling of population age-incidence data, we estimate that 1 (95% confidence limits 0 and 3) of these families is expected to meet the Amsterdam criteria I for HNPCC due to chance clustering of colorectal cancer. © 2001 Cancer Research Campaign http://www.bjcancer.com Nature Publishing Group 2001-04 /pmc/articles/PMC2363862/ /pubmed/11308258 http://dx.doi.org/10.1054/bjoc.2000.1717 Text en Copyright © 2001 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Katballe, N
Bentzen, S M
Christensen, M
Wikman, F P
Ørntoft, T
Laurberg, S
Role of chance in familial aggregation of colorectal cancer
title Role of chance in familial aggregation of colorectal cancer
title_full Role of chance in familial aggregation of colorectal cancer
title_fullStr Role of chance in familial aggregation of colorectal cancer
title_full_unstemmed Role of chance in familial aggregation of colorectal cancer
title_short Role of chance in familial aggregation of colorectal cancer
title_sort role of chance in familial aggregation of colorectal cancer
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363862/
https://www.ncbi.nlm.nih.gov/pubmed/11308258
http://dx.doi.org/10.1054/bjoc.2000.1717
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AT wikmanfp roleofchanceinfamilialaggregationofcolorectalcancer
AT ørntoftt roleofchanceinfamilialaggregationofcolorectalcancer
AT laurbergs roleofchanceinfamilialaggregationofcolorectalcancer

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