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Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Δ Np73L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51

We have recently identified a second p53 -related p73L gene, also referred to as p63 / p51 / p40 / KET gene, which encodes the 2 major isoforms p73L and p51 resulting from different exon usage at their amino terminal regions. Although p73L and p51 are suspected to play oncogenic and tumour suppressi...

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Detalles Bibliográficos
Autores principales: Senoo, M, Tsuchiya, I, Matsumura, Y, Mori, T, Saito, Y, Kato, H, Okamoto, T, Habu, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363892/
https://www.ncbi.nlm.nih.gov/pubmed/11336476
http://dx.doi.org/10.1054/bjoc.2000.1735