Therapy of human non-small-cell lung carcinoma using antibody targeting of a modified superantigen

Superantigens activate T-cells by linking the T-cell receptor to MHC class II on antigen-presenting cells, and novel reactivity can be introduced by fusing the superantigen to a targeting molecule. Thus, an antibody-targeted superantigen, which activates T cells to destroy tumour cells, might be use...

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Detalles Bibliográficos
Autores principales: Forsberg, G, Ohlsson, L, Brodin, T, Björk, P, Lando, P A, Shaw, D, Stern, P L, Dohlsten, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363924/
https://www.ncbi.nlm.nih.gov/pubmed/11437414
http://dx.doi.org/10.1054/bjoc.2001.1891

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