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Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon

Photodynamic diagnosis and especially therapy after sensitization with 5-aminolevulinic acid (ALA) is hampered by limitations of uptake and distribution of ALA due to its hydrophilic nature. Chemical modification of ALA into its more lipophilic esters seems to be promising to overcome these problems...

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Detalles Bibliográficos
Autores principales:	Endlicher, E, Rümmele, P, Hausmann, F, Krieg, R, Knüchel, R, Rath, H C, Schölmerich, J, Messmann, H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363929/ https://www.ncbi.nlm.nih.gov/pubmed/11720447 http://dx.doi.org/10.1054/bjoc.2001.2124

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