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The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients
The purpose of this study was to investigate the effect of the co-solvents Cremophor EL and polysorbate 80 on the absorption of orally administered paclitaxel. 6 patients received in a randomized setting, one week apart oral paclitaxel 60 mg m(−2) dissolved in polysorbate 80 or Cremophor EL. For 3 p...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363961/ https://www.ncbi.nlm.nih.gov/pubmed/11720431 http://dx.doi.org/10.1054/bjoc.2001.2118 |