The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours

To study the prevalence of avascular necrosis in patients receiving chemotherapy for testicular cancer we invited 103 consecutive patients treated by chemotherapy to attend for MRI scan of the hips. Four of 47 (9% (CI 2–20%)) patients scanned and 4/103 (3.8% (CI 1–10%)) of patients invited to partic...

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Autores principales: Cook, A M, Dzik-Jurasz, A S K, Padhani, A R, Norman, A, Huddart, R A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363966/
https://www.ncbi.nlm.nih.gov/pubmed/11742478
http://dx.doi.org/10.1054/bjoc.2001.2155
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author Cook, A M
Dzik-Jurasz, A S K
Padhani, A R
Norman, A
Huddart, R A
author_facet Cook, A M
Dzik-Jurasz, A S K
Padhani, A R
Norman, A
Huddart, R A
author_sort Cook, A M
collection PubMed
description To study the prevalence of avascular necrosis in patients receiving chemotherapy for testicular cancer we invited 103 consecutive patients treated by chemotherapy to attend for MRI scan of the hips. Four of 47 (9% (CI 2–20%)) patients scanned and 4/103 (3.8% (CI 1–10%)) of patients invited to participate in the study had evidence of avascular necrosis. As not all patients in the study had completed the at risk period this equates to a 3-year actuarial risk of 6.3% (95% confidence limits (CI) 2.4–16.1). These data suggest that avascular necrosis is an uncommon but significant complication of chemotherapy including steroids as anti-emetics. © 2001 Cancer Research Campaign http://www.bjcancer.com
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spelling pubmed-23639662009-09-10 The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours Cook, A M Dzik-Jurasz, A S K Padhani, A R Norman, A Huddart, R A Br J Cancer Regular Article To study the prevalence of avascular necrosis in patients receiving chemotherapy for testicular cancer we invited 103 consecutive patients treated by chemotherapy to attend for MRI scan of the hips. Four of 47 (9% (CI 2–20%)) patients scanned and 4/103 (3.8% (CI 1–10%)) of patients invited to participate in the study had evidence of avascular necrosis. As not all patients in the study had completed the at risk period this equates to a 3-year actuarial risk of 6.3% (95% confidence limits (CI) 2.4–16.1). These data suggest that avascular necrosis is an uncommon but significant complication of chemotherapy including steroids as anti-emetics. © 2001 Cancer Research Campaign http://www.bjcancer.com Nature Publishing Group 2001-11 /pmc/articles/PMC2363966/ /pubmed/11742478 http://dx.doi.org/10.1054/bjoc.2001.2155 Text en Copyright © 2001 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Cook, A M
Dzik-Jurasz, A S K
Padhani, A R
Norman, A
Huddart, R A
The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
title The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
title_full The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
title_fullStr The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
title_full_unstemmed The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
title_short The prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
title_sort prevalence of avascular necrosis in patients treated with chemotherapy for testicular tumours
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363966/
https://www.ncbi.nlm.nih.gov/pubmed/11742478
http://dx.doi.org/10.1054/bjoc.2001.2155
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