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Activation and activities of the p53 tumour suppressor protein

The p53 tumour suppressor protein inhibits malignant progression by mediating cell cycle arrest, apoptosis or repair following cellular stress. One of the major regulators of p53 function is the MDM2 protein, and multiple forms of cellular stress activate p53 by inhibiting the MDM2-mediated degradat...

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Detalles Bibliográficos
Autores principales:	Bálint, É, Vousden, K H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364002/ https://www.ncbi.nlm.nih.gov/pubmed/11747320 http://dx.doi.org/10.1054/bjoc.2001.2128

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