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Tyrphostin AG 1024 modulates radiosensitivity in human breast cancer cells

Insulin-like growth factor-1 (IGF-1) plays an important growth-promoting effect by activating the PI3K/Akt signalling pathway, inhibiting apoptotic pathways and mediating mitogenic actions. Tyrphostin AG 1024, one selective inhibitor of IGF-1R, was used to evaluate effects on proliferation, radiosen...

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Detalles Bibliográficos
Autores principales:	Wen, B, Deutsch, E, Marangoni, E, Frascona, V, Maggiorella, L, Abdulkarim, B, Chavaudra, N, Bourhis, J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364012/ https://www.ncbi.nlm.nih.gov/pubmed/11747348 http://dx.doi.org/10.1054/bjoc.2001.2171

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