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Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer
Loss of heterozygosity (LOH) on chromosome 18q21 is frequently found in various human cancers, suggesting the presence of tumour suppressor gene(s) in this chromosomal region. DCC is the most likely target of LOH because loss or reduction of DCC expression has been found in many types of cancers. Ho...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364029/ https://www.ncbi.nlm.nih.gov/pubmed/11461076 http://dx.doi.org/10.1054/bjoc.2001.1888 |