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Topographic analysis of K-ras mutations in histologically normal lung tissues and tumours of lung cancer patients

Mutations in the K-ras gene are very common in lung tumours and are implicated in the development of lung cancer, but the timing of their occurrence remains poorly understood. We investigated K-ras mutations in cell samples microdissected by laser capture microscopy at multiple sites from lung tissu...

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Detalles Bibliográficos
Autores principales: Keohavong, P, Mady, H H, Gao, W M, Siegfried, J M, Luketich, J D, Melhem, M F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364035/
https://www.ncbi.nlm.nih.gov/pubmed/11461083
http://dx.doi.org/10.1054/bjoc.2001.1913