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Metabolism and growth inhibition of four retinoids in head and neck squamous normal and malignant cells

Isotretinoin (13- cis -retinoic acid, 13cRA) has proven to be active in chemoprevention of head and neck squamous cell carcinoma (HNSCC). Moreover, both all-trans-retinoic acid (ATRA) and 13cRA induce objective responses in oral premalignant lesions. After binding of retinoids to retinoic acid recep...

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Detalles Bibliográficos
Autores principales:	Klaassen, I, Brakenhoff, R H, Smeets, S J, Snow, G B, Braakhuis, B J M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2001
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364086/ https://www.ncbi.nlm.nih.gov/pubmed/11506507 http://dx.doi.org/10.1054/bjoc.2001.1952

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