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Hypomethylation of the MN/CA9 promoter and upregulated MN/CA9 expression in human renal cell carcinoma

MN/CA9 is a cancer-related gene, frequently activated in human renal cell carcinomas (RCCs). To reveal the activation mechanism, we investigated the relationship between methylation status of the MN/CA9 promoter region and gene expression using 13 human RCCs, and examined the effect of in vitro CpG...

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Detalles Bibliográficos
Autores principales: Cho, M, Uemura, H, Kim, S-C, Kawada, Y, Yoshida, K, Hirao, Y, Konishi, N, Saga, S, Yoshikawa, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364093/
https://www.ncbi.nlm.nih.gov/pubmed/11506497
http://dx.doi.org/10.1054/bjoc.2001.1951