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Hypomethylation of the MN/CA9 promoter and upregulated MN/CA9 expression in human renal cell carcinoma
MN/CA9 is a cancer-related gene, frequently activated in human renal cell carcinomas (RCCs). To reveal the activation mechanism, we investigated the relationship between methylation status of the MN/CA9 promoter region and gene expression using 13 human RCCs, and examined the effect of in vitro CpG...
Autores principales: | Cho, M, Uemura, H, Kim, S-C, Kawada, Y, Yoshida, K, Hirao, Y, Konishi, N, Saga, S, Yoshikawa, K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364093/ https://www.ncbi.nlm.nih.gov/pubmed/11506497 http://dx.doi.org/10.1054/bjoc.2001.1951 |
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