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Pemetrexed disodium in recurrent locally advanced or metastatic squamous cell carcinoma of the head and neck
This phase II study determined response rate of patients with locally advanced or metastatic head and neck cancer treated with pemetrexed disodium, a new multitargeted antifolate that inhibits thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyl transferase. 35 patient...
Autores principales: | Pivot, X, Raymond, E, Laguerre, B, Degardin, M, Cals, L, Armand, J P, Lefebvre, J L, Gedouin, D, Ripoche, V, Kayitalire, L, Niyikiza, C, Johnson, R, Latz, J, Schneider, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364119/ https://www.ncbi.nlm.nih.gov/pubmed/11531245 http://dx.doi.org/10.1054/bjoc.2001.2010 |
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