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Telomerase reverse transcriptase and telomeric-repeat binding factor protein 1 as regulators of telomerase activity in pancreatic cancer cells
Telomerase adds hexameric repeats of 5′-TTAGGG-3′ termed telomeres to ends of chromosomal DNA. This enzyme has been implicated in cellular immortalization and cellular senescence. Recently, a number of relevant genes have been cloned, including these encoding three major components of human telomera...
Autores principales: | Yajima, T, Yagihashi, A, Kameshima, H, Kobayashi, D, Hirata, K, Watanabe, N |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364122/ https://www.ncbi.nlm.nih.gov/pubmed/11531263 http://dx.doi.org/10.1054/bjoc.2001.1954 |
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