Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy

Among 4380 children born in 1987–1997 of women with a diagnosis of diabetes and alive at the age of one, 10 were registered in the Swedish Cancer Registry before the end of 1998. The odds ratio for having a childhood cancer after maternal diabetes, stratified for year of birth, maternal age, parity,...

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Autores principales: Westbom, L, Åberg, A, Källén, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2002
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364171/
https://www.ncbi.nlm.nih.gov/pubmed/11953852
http://dx.doi.org/10.1038/sj.bjc.6600192
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author Westbom, L
Åberg, A
Källén, B
author_facet Westbom, L
Åberg, A
Källén, B
author_sort Westbom, L
collection PubMed
description Among 4380 children born in 1987–1997 of women with a diagnosis of diabetes and alive at the age of one, 10 were registered in the Swedish Cancer Registry before the end of 1998. The odds ratio for having a childhood cancer after maternal diabetes, stratified for year of birth, maternal age, parity, multiple birth, and 500 g birth weight class was 2.25 (95%CI 1.22–4.15). Among 5842 children born during the period 1973–1997 whose mothers had other auto-immune diseases (SLE, rheumatoid arthritis, Crohn, ulcerous colitis, multiple sclerosis or thyroiditis), the number of observed childhood cancers (9) was close to that expected (8.5). Maternal diabetes but not other auto-immune diseases may be a risk factor for childhood cancer. British Journal of Cancer (2002) 86, 1078–1080. DOI: 10.1038/sj/bjc/6600192 www.bjcancer.com © 2002 Cancer Research UK
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spelling pubmed-23641712009-09-10 Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy Westbom, L Åberg, A Källén, B Br J Cancer Epidemiology Among 4380 children born in 1987–1997 of women with a diagnosis of diabetes and alive at the age of one, 10 were registered in the Swedish Cancer Registry before the end of 1998. The odds ratio for having a childhood cancer after maternal diabetes, stratified for year of birth, maternal age, parity, multiple birth, and 500 g birth weight class was 2.25 (95%CI 1.22–4.15). Among 5842 children born during the period 1973–1997 whose mothers had other auto-immune diseases (SLE, rheumatoid arthritis, Crohn, ulcerous colitis, multiple sclerosis or thyroiditis), the number of observed childhood cancers (9) was close to that expected (8.5). Maternal diabetes but not other auto-immune diseases may be a risk factor for childhood cancer. British Journal of Cancer (2002) 86, 1078–1080. DOI: 10.1038/sj/bjc/6600192 www.bjcancer.com © 2002 Cancer Research UK Nature Publishing Group 2002-04-08 /pmc/articles/PMC2364171/ /pubmed/11953852 http://dx.doi.org/10.1038/sj.bjc.6600192 Text en Copyright © 2002 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Westbom, L
Åberg, A
Källén, B
Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
title Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
title_full Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
title_fullStr Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
title_full_unstemmed Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
title_short Childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
title_sort childhood malignancy and maternal diabetes or other auto-immune disease during pregnancy
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2364171/
https://www.ncbi.nlm.nih.gov/pubmed/11953852
http://dx.doi.org/10.1038/sj.bjc.6600192
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